Isotretinoin (Roaccutane) Isotretinoin is a medicine used to treat severe acne. It's only available on prescription. Roaccutane is indicated for the treatment of severe forms of acne (nodular or conglobate acne, or acne at risk of permanent scarring), and acne which has failed to respond to standard therapies with systemic antibacterials and topical therapy. Description Isotretinoin is used to treat severe, disfiguring nodular acne. It should be used only after other acne medicines or antibiotics have been tried and have failed to help the acne. Isotretinoin may also be used to treat other skin diseases as determined by your doctor. Isotretinoin must not be used to treat women who are able to bear children unless other forms of treatment have been. Find patient medical information for Isotretinoin on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Accutane (isotretinoin) is a form of vitamin A and is used to treat severe nodular acne. Includes Accutane side effects, interactions and indications. Isotretinoin (oral): side effects, dosage, interactions, FAQs, reviews. Used for: acne, acute nonlymphocytic leukemia, granuloma annulare, melanoma, metastatic, and more. Roaccutane is a brand-name medication containing the active ingredient isotretinoin, a systemic retinoid derived from Vitamin A. It is primarily used for the treatment of severe forms of acne that have not responded adequately to conventional therapies, such as topical creams or oral antibiotics. By June 2009, Roche discontinued the Accutane brand amid falling market share and rising costs from personal injury lawsuits. [104][105] However, Roche's overseas affiliates continue to sell isotretinoin as Roaccutane. [106] Isotretinoin Capsule Information Information on Isotretinoin Isotretinoin is marketed as Absorica, Absorica LD, Claravis, Amnesteem, Myorisan, and Zenatane, and is sometimes referred to by its. Roaccutane is a synthetic retinoid which reduces sebaceous gland size and inhibits sebum production. It also regulates cell proliferation and differentiation and has dermal anti-inflammatory effect.